CEOS Vascular Medicine and Research

Biography:

Sudarshan Bhattacharjee A graduate of Nankai University, Dr. Hong Chen completed her Ph.D. and postdoctoral training at the Yale University School of Medicine in the laboratory of Dr. Pietro De Camilli, where she discovered a family of endocytic adaptor proteins called epsins. Dr. Chen worked in the Cardiovascular Biology Research Program at the University of Oklahoma Health Sciences Center before moving to Boston Children's Hospital and Harvard Medical School in 2015.Her group continues to study epsins and other endocytic adaptors for their impact on disease initiation and progression. Dr. Chen received the Irvine H. Page Young Investigator Research Award from the American Heart Association (AHA) in 2013, the AHA Established Investigator Award in 2015 and the 2018 AHA Alan T Hirsch MD Mid-Career Award in Vascular Medicine. She is currently serving on the AHA Arteriosclerosis, Thrombosis, and Vascular Biology Woman’s Leadership Committee and serves as a grant reviewer for the AHA and the National Institutes of Health (NIH).

Research Interest:

Sudarshan Bhattacharjee My research interest lies in investigating the molecular mechanisms underlying pathological angiogenesis and its implications in vascular diseases, particularly in the context of diabetes. Building on my extensive background in metabolic dysregulation and lipotoxicity associated with obesity-induced insulin resistance, I aim to elucidate the role of endocytic adaptor proteins, such as Dab2 and Epsins in modulating VEGFR2-mediated signaling pathways during angiogenesis.